The 25 Best Sibling Duos In Anime History

Edward and Alphonse Elric are gifted alchemist brothers and the main protagonists of Fullmetal Alchemist. After losing their mother and failing to revive her through alchemy, a tragic accident costs Ed his arm and leg. To save Al's life, Ed sacrifices his arm again to bind Al's soul to a suit of armor. This creates an unusual sibling dynamic as the older brother Ed acts as caretaker and guide to Al in his hulking armored body. Their bond is tested through their travels and battles to try to regain their original bodies.

Rin and Yukio Okumura are twin brothers raised at a monastery in Blue Exorcist. While Rin inherits their biological father Satan's blue flames and demonic powers, Yukio displays no powers but becomes a remarkably gifted exorcist. Yukio is sent to guide Rin in controlling his volatile abilities amidst their strained relationship and Rin's resentment at Yukio's exorcist skills and normal life. But they support each other against the forces threatening the world.

In No Game No Life, Sora and Shiro form a powerful sibling gaming duo, relying on each other's strengths and never playing games alone. Their unbreakable bond helps them thrive in Disboard where everything is decided by games. Sora's cunning and Shiro's logic make them an unbeatable pair who aim to unite the sixteen races against the gods.

The Hitachiin twins, Hikaru and Kaoru, play up their closeness for their fans at Ouran High School and are practically inseparable. However, their habit of isolating themselves is challenged when Haruhi befriends them. As they open up to her and others, the twins slowly start to develop more individuality outside of their joint identity.

Kill la Kill's Kiryūin sisters Satsuki and Ryūko initially have a hostile dynamic, as Satsuki rules the elite Honnōji Academy where Ryūko searches for her father's killer. But they later ally against their shared mother Ragyō, who was responsible for their father's murder and experiments on Life Fibers. Their bond strengthens after overcoming Ragyō.

Yūichirō Hyakuya joins the Moon Demon Company in Seraph of the End on a quest to exterminate vampires after they wipe out his orphanage family, including his sickly younger brother Mikaela. Yūichirō remains driven by this vendetta and the desire to avenge Mikaela. But later encounters with Mikaela, now a vampire, complicate his motivations.